The anti life equation enslaved the world by being release on the internet, Darkseid and the New gods were reborn in the bodies of humans, Wonder Woman, Batwoman, Giganta, and Catwoman became Darkseid's new furies, Granny goodness infected the mind of an alpha lantern, tried to infect the Guardian's power battery.
Lois Lane was almost killed, which sent superman on a quest to save her while all the bullshit went down. Libra enslaved the entirety of the society of villains as the "one true prophet of anti life". Lex Luthor has betrayed them and is trying to help.
The Superhuman society has been fractured, with many of them falling to anti life.
Lots of bad shit.