One bit I'm hoping that the remake will remember at least as a background detail in the game's ending: Dyne's/Eleanor's pendant.
In the original game (and indeed even in the post-OG Compilation material) the pendant is entirely forgotten after the Corel Prison scenario. In the remake I hope it gets addressed later on.
I picture two possible scenarios.
A) Barret gives the pendant to Marlene off-screen at the end of disc 2 and then in the Meteorfall cinematic we see the pendant either on Marlene or in her room when the camera pans to Kalm.
B) Barret holds on to the pendant throughout the team's trek down into the Northern Crater. He would be keeping it as assurance that he'll survive, and that indeed there will be a planet left to survive in, because he promised to give the pendant to Marlene.
To some degree the pendant is an uncomfortable element to deal with. It is tainted by having been worn by a mad killer for years. That's why I suggest that the pendant may not necessarily be worn by Marlene. Regardless of the complicated aspects of the pendant I do hope that it is brought back near the game's ending.